Jocher, Jessica; Edenhofer, Fiona C.; Janssen, Philipp; Müller, Stefan; Lopez-Parra, Dana C.; Geuder, Johanna; Enard, Wolfgang (2024): Generation and characterization of three fibroblast-derived Rhesus Macaque induced pluripotent stem cell lines. Stem Cell Research, 74: 103277. ISSN 18735061
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Abstract
Cross-species comparisons using pluripotent stem cells from primates are crucial to better understand human biology, disease, and evolution. An important primate model is the Rhesus macaque (Macaca mulatta), and we reprogrammed skin fibroblasts from a male individual to generate three induced pluripotent stem cell (iPSC) lines. These cells exhibit the typical ESC-like colony morphology, express common pluripotency markers, and can differentiate into cells of the three germ layers. All generated iPSC lines can be cultured under feeder-free conditions in commercially available medium and are therefore valuable resources for cross-species comparisons.
| Doc-Type: | Article (LMU) |
|---|---|
| Organisational unit (Faculties): | 19 Biology |
| DFG subject classification of scientific disciplines: | Life sciences |
| Date Deposited: | 10. Apr 2024 12:26 |
| Last Modified: | 10. Apr 2024 12:26 |
| URI: | https://oa-fund.ub.uni-muenchen.de/id/eprint/1180 |
| DFG: | Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) - 458247426 |
| DFG: | Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) - 491502892 |
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