Jocher, Jessica; Edenhofer, Fiona C.; Janssen, Philipp; Müller, Stefan; Lopez-Parra, Dana C.; Geuder, Johanna; Enard, Wolfgang (2024): Generation and characterization of three fibroblast-derived Rhesus Macaque induced pluripotent stem cell lines. Stem Cell Research, 74: 103277. ISSN 18735061
![[thumbnail of 1-s2.0-S1873506123002635-main.pdf]](https://oa-fund.ub.uni-muenchen.de/style/images/fileicons/text.png "1-s2.0-S1873506123002635-main.pdf")
Creative Commons Namensnennung - Nicht-Kommerziell - Keine Bearbeitung (CC BY-NC-ND)
Veröffentlichte Publikation
1-s2.0-S1873506123002635-main.pdf
Abstract
Cross-species comparisons using pluripotent stem cells from primates are crucial to better understand human biology, disease, and evolution. An important primate model is the Rhesus macaque (Macaca mulatta), and we reprogrammed skin fibroblasts from a male individual to generate three induced pluripotent stem cell (iPSC) lines. These cells exhibit the typical ESC-like colony morphology, express common pluripotency markers, and can differentiate into cells of the three germ layers. All generated iPSC lines can be cultured under feeder-free conditions in commercially available medium and are therefore valuable resources for cross-species comparisons.
| Dokumententyp: | Artikel (LMU) |
|---|---|
| Organisationseinheit (Fakultäten): | 19 Biologie |
| DFG-Fachsystematik der Wissenschaftsbereiche: | Lebenswissenschaften |
| Veröffentlichungsdatum: | 10. Apr 2024 12:26 |
| Letzte Änderung: | 10. Apr 2024 12:26 |
| URI: | https://oa-fund.ub.uni-muenchen.de/id/eprint/1180 |
| DFG: | Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 458247426 |
| DFG: | Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 491502892 |
- Publikation bearbeiten