Hörner‐Schmid, Lina ORCID: 0000-0002-4677-7873; Gareis, Hannah
ORCID: 0000-0002-5740-6023; Palić, Jelena; Schulz, Bianka
(2024):
Influence of acclimatization time on barometric whole‐body plethysmography in cats with lower airway disease.
Journal of Veterinary Internal Medicine, 38 (5).
pp. 2654-2663.
ISSN 0891-6640
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Abstract
Background:
Barometric whole-body plethysmography (BWBP) is used as a noninvasive method to assess lung function in cats with lower airway disease (LAD). The duration of the acclimatization period in the measuring chamber varies between the studies.
Objectives:
To assess the influence of acclimatization time on variables indicative of lung function.
Animals:
Twenty-four client-owned cats with LAD and 8 healthy cats.
Methods:
In the prospective case-control study for each cat, a 30-minute dataset was collected. Data for the three 10-minute periods were statistically compared.
Results:
The variables pause (T1 median: 0.8, range: [0.7-1]; T3: 0.9 [0.8-1.1]; P ≤ .01), peak inspiratory flow (PIF; T1: 84.9 [71.6-112.7]; T3: 75 [63.6-108.3]; P ≤ .001), peak expiratory flow (PEF; T1: 53.2 [41.5-76.6]; T3: 42.5 [34.6-57.8]; P ≤ .01), and a quotient of PEF and expiratory flow at 50% expired volume (PEF/EF50; T1: 1.2 [1.1-1.4]; T3: 1.2 [1.1-1.5]; P ≤ .01) varied significantly between first and third time period in cats with LAD. In healthy cats PIF (T1: 76.4 [66.3-85.2]; T2: 69.5 [58.3-85.2]; P ≤ .01), PEF (T1: 40 [32.8-58.6]; T2: 34.3, [29.8-44.6]; P ≤ .01), and PEF/EF50 (T1: 13.1 [11.6-14.6]; T3: 13.6 [12.4-16.3]; P ≤ .01) changed significantly between first and second time period. Enhanced pause did not change significantly in either group.
Conclusions and Clinical Importance:
Acclimatization time has a significant influence on multiple variables in BWBP. Manual correction of the data for tidal breathing flow-volume loop might be necessary.
Dokumententyp: | Artikel (LMU) |
---|---|
Organisationseinheit (Fakultäten): | 08 Tiermedizin > Zentrum für Klinische Tiermedizin > Medizinische Kleintierklinik |
DFG-Fachsystematik der Wissenschaftsbereiche: | Lebenswissenschaften |
Veröffentlichungsdatum: | 05. Mai 2025 08:55 |
Letzte Änderung: | 05. Mai 2025 08:55 |
URI: | https://oa-fund.ub.uni-muenchen.de/id/eprint/1735 |
DFG: | Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 491502892 |