Efects of robotic-assisted early mobilization versus conventional mobilization in intensive care unit patients: prospective interventional cohort study with retrospective control group analysis

Huebner, Lucas; Warmbein, Angelika; Scharf, Christina; Schroeder, Ines; Manz, Kirsi Marjaana; Rathgeber, Ivanka; Gutmann, Marcus; Biebl, Johanna; Mehler-Klamt, Amrei; Huber, Jana; Eberl, Inge; Kraft, Eduard; Fischer, Uli ; Zoller, Michael (2024): Efects of robotic-assisted early mobilization versus conventional mobilization in intensive care unit patients: prospective interventional cohort study with retrospective control group analysis. Effects of robotic-assisted early mobilization versus conventional mobilization in intensive care unit patients: prospective interventional cohort study with retrospective control group analysis, 28: 112. pp. 1-5. ISSN 1364-8535

Abstract

Background
Approximately one in three survivors of critical illness suffers from intensive-care-unit-acquired weakness, which increases mortality and impairs quality of life. By counteracting immobilization, a known risk factor, active mobilization may mitigate its negative effects on patients. In this single-center trial, the effect of robotic-assisted early mobilization in the intensive care unit (ICU) on patients’ outcomes was investigated.

Methods
We enrolled 16 adults scheduled for lung transplantation to receive 20 min of robotic-assisted mobilization and verticalization twice daily during their first week in the ICU (intervention group: IG). A control group (CG) of 13 conventionally mobilized patients after lung transplantation was recruited retrospectively. Outcome measures included the duration of mechanical ventilation, length of ICU stay, muscle parameters evaluated by ultrasound, and quality of life after three months.

Results
During the first week in the ICU, the intervention group received a median of 6 (interquartile range 3–8) robotic-assisted sessions of early mobilization and verticalization. There were no statistically significant differences in the duration of mechanical ventilation (IG: median 126 vs. CG: 78 h), length of ICU stay, muscle parameters evaluated by ultrasound, and quality of life after three months between the IG and CG.

Conclusion
In this study, robotic-assisted mobilization was successfully implemented in the ICU setting. No significant differences in patients’ outcomes were observed between conventional and robotic-assisted mobilization. However, randomized and larger studies are necessary to validate the adequacy of robotic mobilization in other cohorts.

Trial registration: This single-center interventional trial was registered in clinicaltrials.gov as NCT05071248 on 27/08/2021.

• Dokumententyp: Artikel (Klinikum der LMU)
• Organisationseinheit (Fakultäten): 07 Medizin > Klinikum der LMU München > Klinik für Anaesthesiologie
• DFG-Fachsystematik der Wissenschaftsbereiche: Lebenswissenschaften
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 491502892