Fine Particulate Exposure During Pregnancy Impacts on Perinatal Complications in Deeply Phenotyped Preterm Infants With Significant Immaturity

Johansson, Caroline; Kraus, Yvonne; Sanchez, Juan David Henao; Schubert, Benjamin; Wolf, Kathrin; Voss, Carola; Stoeger, Tobias; Seegmüller, Tanja; Flemmer, Andreas W.; Förster, Kai; Standl, Marie; Hilgendorff, Anne (2026): Fine Particulate Exposure During Pregnancy Impacts on Perinatal Complications in Deeply Phenotyped Preterm Infants With Significant Immaturity. Pulmonary Circulation, 16 (2): e70320. ISSN 2045-8940

Abstract

The identification of ubiquitous risk factors determining long-term morbidity is crucial in infants born prematurely when aiming to develop prevention strategies. In a cohort of deeply phenotyped infants born before 32 weeks gestational age, we successfully demonstrate that exposure to fine particulate matter during pregnancy is associated with increased odds of preeclampsia and altered birth weight percentiles, highlighting potential underlying effects on vascular and metabolic pathology in relation to the degree of immaturity.

• Dokumententyp: Artikel (Klinikum der LMU)
• Organisationseinheit (Fakultäten): 07 Medizin > Klinikum der LMU München > Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital > Abteilung Kinderkardiologie und Pädiatrische Intensivmedizin
• DFG-Fachsystematik der Wissenschaftsbereiche: Lebenswissenschaften
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 491502892
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 491676693
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 321812289