Outcomes and associated factors of revision procedures after failed total ankle arthroplasty: a comparative cohort analysis

Pfahl, Kathrin; Eder, Julia; Simon, Dominic; Beckers, Gautier; Holzapfel, Boris Michael; Walther, Markus (2026): Outcomes and associated factors of revision procedures after failed total ankle arthroplasty: a comparative cohort analysis. Archives of Orthopaedic and Trauma Surgery, 146: 145. ISSN 1434-3916

Abstract

Introduction

After failed total ankle arthroplasty (TAA), revision arthrodesis (RAA) and revision arthroplasty (RTAA) are treatment options, but comparative outcome data remain limited. The aim of this study was to compare mid-term survival of RAA and RTAA after failed primary TAA and to explore clinical and radiographic factors associated with failure.

Materials and methods

In this retrospective cohort study, 124 patients (RAA = 72, RTAA = 52) were reviewed after failed TAA between 2006 and 2020, with a minimum follow-up of 12 months. Kaplan-Meier analysis and Cox regression were used to assess survival, and decision tree models were used as exploratory tools to identify factors associated with failure.

Results

Mean follow-up was 71.6 ± 42.7 months. Surgical failure occurred in 6.45% of patients, with no significant difference (RAA 6.9%, RTAA 5.8%). Five-year survival was slightly higher for RTAA (97% vs. 93%), although durability decreased beyond 87 months. Female sex, higher BMI, and younger age were associated with failure after RAA, whereas large periprosthetic cysts and elevated BMI were related to failure after RTAA.

Conclusions

RAA and RTAA demonstrate comparable mid-term survival after failed TAA. Revision strategy selection should be individualized, considering bone stock, patient characteristics, and failure patterns.

• Dokumententyp: Artikel (Klinikum der LMU)
• Organisationseinheit (Fakultäten): 07 Medizin > Klinikum der LMU München > MUM - Muskuloskelettales Universitätszentrum München
• DFG-Fachsystematik der Wissenschaftsbereiche: Lebenswissenschaften
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 491502892